OLM

Omega-3 Fatty Acids Protect Cognitive Function in Aging Adults!

In neurodegenerative diseases such as Alzheimer’s disease (AD) or mild cognitive impairment (pre-dementia phase of AD) changes in cognitive function and memory decline occur quicker than in normal aging. In this study, researchers looked at the effects of 2,200 mg of Omega-3 (n3) fatty acids (FA) taken daily for six months on memory function. Using LOCATO, a robust and sensitive tool for assessing object-location memory (OLM) in older adults to evaluate the impact of n3-FA on memory and learning formation, they conducted a double-blind placebo-controlled proof-of-concept study. 44 healthy female participants (50-74 yrs) completed before and after OLM-task (testing). As secondary outcome parameters, performance in Rey Auditory Verbal Learning Test (AVLT), dietary habits, omega-3-index, and other blood-derived parameters were assessed. They received either n3- FA or placebo for 26 weeks. Omega-3 index increased significantly in the n3-FA group compared to placebo. Recall of object locations was significantly better after n3-FA supplementation compared to placebo, although the AVLT was not significantly affected. This study provides further evidence that n3-FA exert positive effects on memory functions in healthy older adults, and the findings suggest novel strategies to maintain cognitive function into old age.

Külzow N, et al. Impact of Omega-3 Fatty Acid Supplementation on Memory Functions in Healthy Older Adults. Journal of Alzheimer’s Disease. Feb 10 2016 doi:10.3233/JAD-150886

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