Review Chios

Mastic Gum for H. Pylori?

Mastic gum is the resin of Pistacia lentiscus. Production of Mastic is limited and its rarity makes it rather expensive. It has been used for over 2,500 years in traditional Greek medicine for treating diseases such as gastralgia and peptic ulcers. Modern research has documented Mastic’s beneficial action against H. Pylori, considered the main cause for gastric ulcers(1). Studies using Mastic have characterized it as a wide-range therapeutic agent demonstrating antimicrobial and antifungal activities among others. Additional research supports the numerous beneficial effects of Mastic gum, including the eradication of bacterial and fungi that may cause peptic ulcers, inhibiting the production of pro-inflammatory substances by activated macrophages, and even the inhibition of growth of human tumors xenografted in immune-deficient mice(2). Mastic gum has been shown to significantly reduce the intensity of gastric mucosal damage induced by pyloric ligation, aspirin, phenylbutozone and reserpine via its antisecretory and cytoprotective activities(3). The wide pharmacological activities support Mastic’s beneficial effects in gastrointestinal disorders.

1. Paraschos S, et al. Chios gum mastic: A review of its biological activities. Curr Med Chem. 2012;19(14):2292-302.
2. Dimas KS, et al. Review: Chios mastic gum: a plant-produced resin exhibiting numerous diverse pharmaceutical and biomedical properties. In Vivo. 2012 Sep-Oct;26(5):777-85.
3. Bozorgi M, et al. Five Pistacia species (P. vera, P. atlantica, P. terebinthus, P. khinjuk, and P. lentiscus): a review of their traditional uses, phytochemistry, and pharmacology. Scientific World Journal. 2013 Dec 15;2013:219815.


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