Omega-3 Fatty Acid Supplementation

Omega-3 Fatty Acids Protect Cognitive Function in Aging Adults!

In neurodegenerative diseases such as Alzheimer’s disease (AD) or mild cognitive impairment (pre-dementia phase of AD) changes in cognitive function and memory decline occur quicker than in normal aging. In this study, researchers looked at the effects of 2,200 mg of Omega-3 (n3) fatty acids (FA) taken daily for six months on memory function. Using LOCATO, a robust and sensitive tool for assessing object-location memory (OLM) in older adults to evaluate the impact of n3-FA on memory and learning formation, they conducted a double-blind placebo-controlled proof-of-concept study. 44 healthy female participants (50-74 yrs) completed before and after OLM-task (testing). As secondary outcome parameters, performance in Rey Auditory Verbal Learning Test (AVLT), dietary habits, omega-3-index, and other blood-derived parameters were assessed. They received either n3- FA or placebo for 26 weeks. Omega-3 index increased significantly in the n3-FA group compared to placebo. Recall of object locations was significantly better after n3-FA supplementation compared to placebo, although the AVLT was not significantly affected. This study provides further evidence that n3-FA exert positive effects on memory functions in healthy older adults, and the findings suggest novel strategies to maintain cognitive function into old age.

Külzow N, et al. Impact of Omega-3 Fatty Acid Supplementation on Memory Functions in Healthy Older Adults. Journal of Alzheimer’s Disease. Feb 10 2016 doi:10.3233/JAD-150886

0

Fish Oil for Healthy Community Dwelling Senior Women!

As we age, we typically experience a decrease in muscle mass and metabolic rate and an increase in fat mass, thereby predisposing older adults to chronic disease and functional impairment. The result is an eventual decrease in the quality of life. Researchers from the Department of Human Health and Nutritional Sciences at the University of Guelph in Canada, conducted a study to evaluate the effect of fish oil (FO) supplementation in a cohort of healthy, community-dwelling older females. They evaluated 1) metabolic rate and substrate oxidation at rest and during exercise; 2) resting blood pressure and exercise heart rates; 3) body composition; 4) strength and physical function, and; 5) blood measures of insulin, glucose, CRP and triglycerides. Twenty-four females (66 ± 1 yr) were randomly assigned to receive either 3g/day of EPA and DHA or a placebo for 12 weeks. Exercise measurements were taken before and after 12 weeks and resting metabolic measures were made before and at 6 and 12 weeks. Results showed that FO supplementation significantly increased resting metabolic rate by 14%, energy expenditure during exercise by 10%, and the rate of fat oxidation during rest by 19% and during exercise by 27%. Additionally, FO consumption lowered triglycerides by 29%, increased lean mass by 4%, and functional capacity by 7%. No changes occurred in the placebo group.

Logan SL, Spriet LL. Omega-3 Fatty Acid Supplementation for 12 Weeks Increases Resting and Exercise Metabolic Rate in Healthy Community-Dwelling Older Females. PLoS ONE 10 (12): e0144828. doi:10.1371/journal.pone.0144828 (Dec 17, 2015)

2

Biotics Research Corporation has been a leading manufacturer of specially designed nutritional products for over thirty years. Our mission remains constant: to be the benchmark of excellence in nutritional science, technology and service, providing the clinician with reliable, innovative products of superior quality as well as the highest level of customer service.

Click here to subscribe to the The Bio-Blog via email!

Click here
to become our Fan on Facebook!