by Keith Steber
Why you may need NAC: Mitochondria are “unusual organelles” within cells. They are
commonly referred to as “the powerhouse of cells.” They are unusual in that they are
surrounded by a double membrane and contain their own genome. Mitochondrial division is
stimulate by energy demand, so cells with an increased energy need, such as those found in heart, brain and muscle tissues, contain greater numbers of these mitochondria organelles. Cellular
energy production relies on proper mitochondrial function. Due to changes in mitochondria that occur as we age, cells have less ability to produce energy (ATP) from a process known as phosphorylation. Fatigue and other unwanted conditions are associated with mitochondrial dysfunction.
Why your healthcare practitioner recommends NAC from Biotics Research:
NAC is a precursor for the production of Glutathione (GSH), an important intracellular
antioxidant, and a critical component of the immune system. NAC also exhibits its own
antioxidant properties, which contribute to the protection of mitochondrial proteins. NAC has been shown to improve mitochondrial energy production and efficiency. NAC also plays a role in the development of the central nervous system, modulation of gene-expression, and inhibits NF-kappaB activation, which if left unchecked, would result in the initiation of inflammatory processes.
by Keith Steber
Why you may need CoQ-Zyme 30™ or CoQ-Zyme 100 Plus™: Coenzyme Q10 (ubiquinone) is a bright yellow nutrient that is found in every single human cell. Your body requires Coenzyme Q10 (CoQ10) for energy production (ATP), of which all cellular function depends. In our bodies, the highest concentration of CoQ10 is found in the cells of organs with high energy requirements such as heart, liver, kidney, muscles, pancreas and brain. While we get a small amount of CoQ10 from our diet, our bodies make (synthesize) most of our CoQ10. This multi-stage process requires at least eight vitamins, certain trace minerals, and several phytochemicals. A
deficiency of any one of these nutrients may result in a CoQ10 deficiency. Besides its role in cellular energy
production, CoQ10 provides other important functions including its antioxidant capacity and ability to
scavenge free radicals. This results in its ability to protect cell membrane stability, while protecting DNA and LDL from free radical damage. The benefits of CoQ10 administration have been most extensively evaluated in a variety of cardiovascular and neurodegenerative conditions, resulting in patient’s improved quality of life.
Why your healthcare practitioner recommends CoQ-Zyme 30™ and CoQ-Zyme 100 Plus™:
Biotics Research Corporation was the first company to offer CoQ10 as a dietary supplement. In an attempt
to improve the uptake of CoQ10, many companies do things such as mixing it with undesirable chemicals such as polyethylene glycol (think antifreeze). However, Biotics Research employs a proprietary micro-emulsification process (just as Mother Nature uses) using only all natural ingredients to enhance the uptake and utilization
of CoQ10. In fact, Biotics Research conducted and published a double blind clinical study documenting the enhanced absorption of Biotics’ CoQ10 compared to the most common form commercially used by most
companies. The research showed that 30 mg of Biotics’ emulsified CoQ10 (CoQ-Zyme 30™) increased plasma CoQ10
levels by 210% in just four weeks, equivalent to 90-100 mg of the other commonly used form.
by Keith Steber
Why you may need Saccharomyces boulardii: Saccharomyces boulardii (S. boulardii) is a viable yeast, and therefore does not contain any milk products. S boulardii is a true “biotic” or living organism which has been shown to have multiple beneficial affects via improvement of intestinal microbalance when orally administered. S. boulardii is not part of the naturally occurring gut flora, and is not significantly impacted by antibiotics. In fact, S boulardii has been shown to be supportive of antibiotic therapy. Oral administration achieves steady state concentration in the colon within three days, but does not colonize in the intestinal tract. It is typically cleared from the intestinal tract within two to 5 days after discontinuation.
Why your healthcare practitioner recommends Saccharomyces boulardii from Biotics Research.
S. boulardii’s proven benefits in balancing the intestinal microbiology are varied. It functions in the modulation of both innate immunity by activating the complement system, and adaptive immunity by boosting the intestinal secretion of IgA (sIgA). S. boulardii has been shown to inactivate bacterial toxins, stimulate intestinal immune response, and release polyamines, which are essential for normal cell growth and differentiation (a depletion of which is associated with a dramatic alteration in the arrangement of the cytoskeleton). Additionally, S. boulardii secretes “soluble factors” demonstrated to reduce inflammatory responses, and blocks the expression of inflammatory cytokines, such as those secreted during E. coli infection. S. boulardii also enhances the secretion of mucosal immune factors which protect against enteric pathogens, improves tight junction structure, and in dendritic immune cells, increases IL-10, which limits unspecific immune responses by down regulating Th-1 response.
Each capsule of Saccharomyces boulardii contains 235 mg of S bouldardii, supplying a minimum of 4 billion organisms at the time of manufacture, and is both gluten and dairy free.
by Keith Steber
Why you may need Dysbiocide®: Dysbiosis has historically been defined as an imbalance of gastrointestinal microflora, indicating an increase in abnormal flora with a coinciding decrease in normal flora, and an increase in pathogenic organisms and yeast in the lower bowel. The definition has since evolved to what Dr. Alex Vasquez
describes generally as “A relationship of non-acute, non-infectious host microorganisms interactions that
adversely affects the human host.” There are numerous correlations including poor diet, physical and/or
psychological stress, and overuse of antibiotics to name a few. For instance, psychological stress has been
demonstrated to decrease the level of secretory IgA, resulting in decreased mucosal immunity.
Why your healthcare practitioner recommends Dysbiocide® from Biotics Research:
Slected botanicals are well recognized in promoting the health of damaged intestinal tissue resulting
predominately from dysbiosis. For example, the active principals of Stemona sessilifolia root exert antifungal and
antibacterial properties. Artimisia absinthium, whose properties are at least partially attributed to its α-santonin content, is a potent, rapidly acting herb with actions that are cholagogue (inducing bile flow), and therefore digestive, as well as healing in nature. This is attributed to its essential oils and amoroids, which also possess antimicrobial and
antiparasitic properties. Artemisia has also been shown to stimulate bitter receptors. Research has correlated the ingestion of bitter stimuli with an initiation of cellular and molecular responses in the endocrine cells of the GI tract.Anethum graveolens seed is an aromatic herb know for its calming effect on the autonomic nervous and
digestive systems, as well as having carminative and stomachic properties. It also provides an essential oil
containing corvone, limonene and α-phellandrene which possess potent activity against bacteria, fungi and molds.
Hedyotis diffusa is widely used in traditional Chinese medicine. Active principles include anthraquinones,
iridoid glucosides, triterpenoids and flavonoids. Hedyotis has been demonstrated to possess antioxidant,
hepatoprotective and neuroprotective properties.
By virtue of its combination of these and other Eastern and Western herbs, Dysbiocide affords a broad effect,
providing an unfriendly environment for undesirable intestinal organisms.
by Keith Steber
Why you may need A.D.P.®: When modern researchers attempt to unlock Nature’s herbal secrets, they frequently turn to the spices and herbs that have been used for centuries to add zest to a wide range of foods. Interestingly, long before the advent of refrigeration it was recognized that herbs and culinary spices could slow food spoilage – natural antimicrobial principles were obviously at work. Food scientists have become increasingly interested in essential oils and aromatic plants. Attempts are being made to identify the active components of essential oils from spices, among them – the oil of oregano. So far, analysis has
revealed several phenolic compounds including Carvacrol, Thymol, Eugenol, 1,8 cineole, as well as
Rosmarinic acid and other antioxidants. Of these compounds Carvacrol and Thymol are believed to have the greatest biological activity. A.D.P.® has been proven effective against yeast and parasites (Patent # 5,955,086). Further research looking at the mechanism of action is indicating that the active components of oil of oregano adversely affect the ability of various microbial organisms to reproduce.
Why your healthcare practitioner recommends A.D.P.® from Biotics Research: While people have relied on the health promoting properties of oregano oil for hundreds of years, Biotics Research Corporation was able to dramatically improve the delivery system of oil of oregano. Many commercially available oregano oil products vary hugely in potency, additionally tinctures and other liquid forms of the oil may be difficult for many people to take as it leaves much to be desired taste-wise. Furthermore, oil of oregano is mostly absorbed in one region of the small intestine, thus limiting the efficacy of a non-sustained release product in reaching the areas of the small and large intestine more likely to be affected. Each tablet of A.D.P.® supplies a standardized extract of oregano oil (50mg) in a sustained release mechanism as an emulsified form, thus ensuring the ease of dosing and maximizing delivery. A.D.P.® is not recommended for pregnant or lactating women. As always, you can count on Biotics Research to provide you with superior nutritional supplements; the “Best of Science and Nature.
by Keith Steber
Why you may need St. John’s Forte™: In today’s society, feelings of anxiousness and nervousness are quite common. Whether it’s due to poor lifestyle habits, such as poor diet and lack of sleep, or emotional or physical stress, patients are often left feeling listless or lethargic.
Why your healthcare practitioner recommends St. John’s Forte™: St. John’s Forte™
supplies a synergistic combination of botanicals, vitamins, minerals and other active compounds documented to
support normal mood, and providing a beneficial effect on anxiety and nervousness. St. John’s Wort (Hypericum
perforatum L.) is classified as a cooling herb and has a long history of use in traditional Chinese medicine.
Conventional use is focused on unwanted mood patterns. Active constituents include hyperforin and hypericin. Damiana (Turnera diffusa) is traditionally used to support the nervous, endocrine and reproductive systems, and is noted for benefits associated with anxiety and nervousness. Siberian Ginseng (Eleutherococcus senticosus)
functions as an adaptogen and is considered an invigorating tonic. Thiamin is a required component in
carbohydrate metabolism and Riboflavin is an important molecule in intermediary metabolism. Folate is provided, as low folate status has been associated with an elevated score on a depressive symptom questionnaire (PHQ score of ≥ 10). Niacin is a precursor to coenzymes NAD and NADP and aids in proper functioning of the nervous system. P5P (the active form of B6) is an important component in the synthesis of neurotransmitters including GABA, serotonin, dopamine, norepinephrine and epinephrine. B12 is involved in numerous enzymes as a required coenzyme and is essential for the transformation of neurotransmitters and the methylation of compounds in the brain. Biotin is an essential coenzyme for five carboxylasis; deficiency has been associated with depression
and lethargy. Chromium is included for its potentiating action on peripheral insulin. Recent research suggests that magnesium levels may be involved in the mechanism for the progression of depressive mood or stress
perception in relatively healthy adult women. Inositol, an essential component of every cell, is a key ingredient for the membrane lipid phosphatidylinositol, while Choline serves as a precursor for the synthesis of acetylcholine and the membrane phospholipid phosphatidycholine, thereby serving to support cognitive function.
by Keith Steber
Why you may need Neuro-5-HTP Plus™: Stressful or fast-paced lifestyles, compounded by the grossly inferior Standard American Diet (SAD) have resulted in widespread neurotransmitter imbalances which may often manifest as altered mood, sleep disturbances, carbohydrate cravings or weight gain, focal or diffuse muscle pain, and headaches. Tryptophan assimilated into the body is metabolized to the amino acid 5-Hydroxytryptophan
(5-HTP) which is the precursor to the synthesis of 5-hydroxytryptamine, which along with dopamine and norepinephrine, are the three main monoamine neurotransmitters. Commonly referred to as the “feel good” neurotransmitter, it has been established that higher serotonin levels reduce carbohydrate cravings and hunger levels in general. In several weight loss studies it was noted that participants with 5-HTP supplementation were afforded weight loss in excess of one pound per week with almost total elimination of the irritability and excess hunger that can plague dieters. Serotonin levels should be a consideration for those with depression, obesity, carbohydrate sensitivity, fibromyalgia, ADHD, migraine headaches, and insomnia.
Why your healthcare provider recommends Neuro-5-HTP Plus™ from Biotics Research:
Neuro-5-HTP Plus™ combines 5-HTP along with 10 mg of B6 phosphate, 50 mg of niacinamide and 50 mg of the neurologically active amino acid L-theanine. These additional ingredients are present to facilitate the conversion of 5-HTP to serotonin with L-theanine increasing alpha waves in the brain and impacting serotonin and/or dopamine neurotransmitters related to memory and learning. The most commonly reported side effect experienced with 5-HTP is nausea, and this can be avoided by initially using a lesser amount and slowly working up to the dose required. Additionally, 5-HTP is not recommended for use during pregnancy or lactation, and should be avoided by patients with cardiovascular disease or those taking certain medications including MAO inhibitors, SSRIs and other serotonergic drugs. Once again, Biotics Research Corporation brings you “The Best of Science & Nature”.
by Keith Steber
Why you may need DopaTropic® Powder: Vastly complex, the human nervous system coordinates innumerable processes via a host of chemical messengers called neurotransmitters. Neurotransmitters are used for everything from signaling the heart and lungs to function, to enabling the body to sleep so regeneration and repair can occur. Emotions, affect, mood, appetite, and even energy levels are also regulated by neurotransmitters. Unfortunately, neurotransmitters operate within a very narrow confine, and their balance can be easily disrupted by a variety of factors including genetics, immune function, diet, stress, and general chemical toxicity. Dopamine is an excitatory neurotransmitter that is important for regulating physical movement, emotion, and pleasure and motivation centers of the brain. It also plays a neurocognitive role, particularly with memory, problem solving, motivation, learning, and the ability to focus. Additionally, dopamine acts on the sympathetic nervous system, thus it impacts physiological functions such as heart rate, blood pressure, and libido.
Why your healthcare practitioner recommends DopaTropic®
Powder: DopaTropic® Powder is one of the newest additions to the Biotics Research line of fine nutritional supplements and is part of the NeuTropic™ group of products including (PheniTropic™, NeuPerzine®, and DopaTropic® Powder among others). L-Dopa, (aka levodopa; L-3,4-dihydroxyphenylalanine) is a naturally occurring dopamine precursor that is derived from the Mucuna pruriens plant. L-Dopa is an amino acid which is converted to the catecholamine neurotransmitter dopamine. Low levels of dopamine are found in Parkinsons patients, and are associated with addictions, cravings, difficulty with focusing, or with the intake or processing information. Each level teaspoon of DopaTropic® Powder contains 125 mg of L-Dopa that is sweetened with erythritol for fast delivery and ease of use. Erythritol is a natural sugar alcohol that is 60-70% as sweet as sugar, yet it is almost non-caloric, and does not affect blood sugar levels or promote tooth decay. Unlike other sugar alcohols, it is unlikely to cause gastric side effects. It is usually recommended that DopaTropic® Powder be dosed early in the day as it may elicit sleep disturbances if taken before bed. DopaTropic® Powder is not recommended for use during pregnancy or lactation. Nor should it be taken in conjunction with MAOI’s, psychosis medications, blood thinners, diabetic medications, or by patients taking medications for Parkinsons disease.
by Keith Steber
Why you may need NeuPerzine®: Vastly complex, the human nervous system coordinates innumerable processes via, a host of chemical messengers called neurotransmitters. Neurotransmitters are used for everything from signaling the heart and lungs to function, to enabling the body to sleep so regeneration and repair can occur. Emotions, affect, mood, appetite, and even energy levels are also regulated by neurotransmitters. Unfortunately, neurotransmitters operate within a very narrow confine, and their balance can be easily disrupted by a variety of factors including genetics, immune function, diet, stress, and general chemical toxicity. NeuPerzine® contains huperzine A, a powerful acetylcholinesterase inhibitor which makes acetylcholine more readily available in the brain, and according to published research, can enhance memory.
Why your healthcare practitioner recommends NeuPerzine®: When healthcare practitioners have determined that a patients’ neurotransmitters are imbalanced, they may choose to address it in a variety of ways including diet, exercise, and strategic supplementation. NeuPerzine® contains a natural compound extracted from the Huperzia serrata plant. This natural compound has been shown to enhance memory in students1, while pharmaceutical derivatives of this natural compound are currently under study for the treatment of
Alzheimers2. In fact, huperzine A compares favorably to synthetic acetylcholinesterase inhibitors in use with the additional benefit of being an antioxidant and neuroprotective. It has been found to be protective against beta amyloid-mediated oxidative stress and apoptosis. It supports general cognition, global clinical status, behavioral disturbance and functional performance. Once again, Biotics Research brings to you supplements representing “The Best of Science & Nature”.
1. Sun, QQ; Xu, SS; Pan, JL; Guo, HM; Cao, WQ (1999). “Huperzine-A capsules enhance memory and learning performance in 34 pairs of matched adolescent students.”. Zhongguo yao li xue bao = Acta pharmacologica Sinica 20 (7): 601–3
2.Shulgina GI (1986). “On neurotransmitter mechanisms of reinforcement and internal inhibition”. Pavlov J Biol Sci 21 (4): 129–40
by Keith Steber
Why you may need PheniTropic™: The human nervous system is vastly complex as it coordinates
innumerable processes via neurotransmitters. These chemical messengers are required for everything from
signaling the heart and lungs to function, to enabling the body to sleep so regeneration and repair can occur. Emotions, affect, mood, appetite, and even energy levels are also regulated by neurotransmitters. Unfortunately, neurotransmitters operate within a very narrow confine, and their balance can be easily disrupted by a variety
of factors including genetics, immune function, diet, stress, and general chemical exposure. Gamma amino
butyric acid (GABA) is a primary inhibitory neurotransmitter. It is one of the ‘feel good’ neurotransmitters that also includes Serotonin, Dopamine, and Norepinehprine, and it is commonly referred to as the anti-anxiety neurotransmitter.
Why your healthcare practitioner recommends PheniTropic™: Patients with low levels
of GABA often complain of or present with hyperactivity, anxiety, irritability, altered mood, and sleep
difficulties. PheniTropic™ contains beta-Phenyl-gamma-aminobutyric acid (Phenibut), a natural derivative of GABA. Phenibut has been demonstrated to have a calming effect and may assist in instances of stress,
anxiety, and even the improvement of impaired sleep.1 However, due to its derivation of GABA,
PheniTropic™ appears to have no significant negative side effects other than the potential for increased sleepiness in some individuals. These effects were not significant when compared with prescription sleep aids.2 PheniTropic™ should not be taken with alcohol, and it should not be used during pregnancy and/or lactation, or in conjunction with sedatives, MAOIs, sleep aids, or with anxiety or seizure medications.
Shulgina GI (1986). “On neurotransmitter mechanisms of reinforcement and internal inhibition”. Pavlov J Biol Sci 21 (4): 129–40
Lapin I (2001). “Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug”. CNS Drug Rev 7 (4): 471–81)